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Pharma 3.0: Say hello to Creative Disruption
Pharma perceives 'digital' as a disruptive technology, but to survive, it is in the industry's best interest to get on with "the non-traditional entrants", such as the telecoms companies. Why didn't it see this technology coming, and why the reluctance in embracing digitality?
Many of the trends transforming the pharma landscape are ICT-related, but the industry is urged to be less paternalistic in dealing with data-empowered patients and “non-traditional entrants” from the device and ICT industries.
The Ernst & Young report, “Progressions: Pharma 3.0”, gave an insight into pharma’s perception towards the digitally-led “disruptive technologies”, and also revealed the industry’s hesitance in taking the appropriate actions to deal with the issues quickly.
New medical technologies spearheaded by the likes of GE Healthcare and Philips were seen to be the most disruptive, closely followed by e-health or m-health [mobile health] modes of labour driven by Google and Facebook. Non-pharmacy retailers such as Wal-Mart, information technology provided by the likes of Cisco, consumer electronics such as Nintendo and telecommunications also contribute to a significant amount of disruption.
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| Speakers at the Economist Pharma Summit 2010. The main question asked at the event: how does pharma deal with 'disruptive technologies', such as the mobile phone? Reportage: The Economist Pharma Summit 2010 |
The responses were pooled from 33 business development and innovation leaders at 24 companies, including 11 of the top 15 Fortune 500 biotechnology and pharmaceutical companies
The report was launched at The Economist Pharmacy Summit 2010 in February in London, UK.
The same sentiments were also articulated by the pharmacy community at the summit. The choice of words made in speeches, and during coffee breaks, made it clear that digital is a “disruptive technology”, with which any partnership effort might be a “creative challenge” – but it is in industry’s best interest to get on with “the non-traditional entrants” to be effectively competing in the future of the healthcare system.
The pressure is on pharmaceutical companies to get a sense of working at real time as it is entering what Buck-Luce terms “Pharmacy 3.0”. “2.0 is about products,” she explained. “3.0 is about patients”.
The rise of the well-informed ‘superconsumer’ means that the payer/patient demands “outcomes”, not “products”. A payer-centric healthcare service means that the client who wants to pay for services will demand more evidence of the results.
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| "2.0 is about products," Carolyn-Buck Lee of Ernst & Young tells Clinica. "3.0 is about patients". Photo: Salina Christmas |
A change in the mode of labour
The concern is not without foundation. Pre-industrialised social structures in Europe were turned on their heads over two centuries ago not so much because of capital ownership, but because of the change in the form of labour caused by industrialisation.
At the summit, Carolyn Buck-Luce, Global Pharmaceutical Sector Leader, Ernst & Young, explained to us the culture clash between pharmacy and digital.
“The R&D of a drug pipeline could be a 15-year cycle,” she said. “It involves a series of processes, such as discovery, proof of concept, clinical trials in different phases, and marketing in the last phase.”
The prototyping process, she noted, is faster, and is geared towards a shorter product cycle.
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| The telecommunication innovations are considered very 'disruptive' by over 30% of the pharma representtaives surveyed by Ernst & Young Click here to see the bigger chart Source: Ernst & Young Progressions survey 2009, p 17 |
A top-down perspective on technology
The report recommended pharmacy companies consider ‘inter-industry collaborations’ with sectors such as ICT, biotech, device and telecommunications – a suggestion mirrored in the talks given by medical device and telecommunications representatives at the summit.
Despite industry’s awareness of ‘trust issues’ between the pharmacy and the non-traditional entrants, discussions at the summit and in the report were slanted towards the adaptation of “technology-driven changes” rather than trust-building.
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| The survey is insightful, but provides a 'top-down' perspective of on the disruptive technology affecting the pharma industry Reportage: The Economist Pharma Summit 2010 |
At a talk on “Emerging Markets”, Robert Ward, Director, Global Forecasting, Economist Intelligence Unit, emphasised that “technology continues to be the driver of globalisation” and that trend is shifting towards “hyper-globalisation”. It was a top-down perspective but not entirely inaccurate. It was apt for a conference that addresses mainly those at the top of the pharma food chain.
The bottom-up perspective would reveal, however, that digital technology, like any technology, is a sociotechnical system. It operates hand in hand with the way we work, socially. The social cohesion that is built around this technology is the platform that props up an economy. It isn’t just technology that drives hyper-globalisation; it’s societal needs as well.
The summit, however, also gave room to a discussion on hyper-localisation and how the digital practices help pharma to engage at a community level, as opposed to state or enterprise level. This was touched upon by Ranjit Shahani, Country President, Novartis India in “Emerging Markets” and to a large extent, by Jon Achenbaum, Senior Vice President of Bayer Healthcare Diabetes Care in a session entitled “Patients driving healthcare innovations”, which centers on Bayer’s Nintendo-inspired device for “kids”.
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| John Achenbaum of Bayer Healthcare is one of the 'non-traditional entrants' that makes an appearance at the Economist Pharma Summit. This Didget blood monitoring device, which comes with a dongle-based connectivity for mobile data transfer, is co-designed by Bayer and Nintendo for children Reportage: The Economist Pharma Summit 2010 |
‘We didn’t see this coming’’
As reflected in the talks and also in the Ernst & Young survey, the attitude of pharma towards the rise of digitality and the superconsumer it enables is one of surprise – surprise by the sudden speed of which digital technology transforms the pharma business practices.
Why didn’t they see it coming? The sociotechnical system, rooted in a unique type of group cohesion that “is neither economic nor political”, remains hidden from those who try to analyse the phenomenon using the conventional economic and political perspectives.
The ‘misdiagnosis’ is common and is only realised when the disruptive technologies render the mainstream technologies obsolete. Disruptive technologies, and the social behaviour which revolved around the applications, are not monetised and are therefore of no interest to the top-down market researchers, who are supposed to spot the trends. But they are easily identified.
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| The mobile phone, a 'disruptive technology' at work at the Economist conference. Big pharma companies, too busy to concentrate on their product research, don't pay attention to the 'inferior' alternatives until it's too late Reportage: The Economist Pharma Summit 2010 |
A disruptive technology is inferior to the mainstream alternative and is adopted by a segment of consumers that don’t make big bucks out of it. (2) In his book, “The Innovator's Dilemma: When New Technologies Cause Great Firms to Fail”, economist Clayton M Christensen provided a set of examples which should help us understand the mainstream / disruptive binary: ‘hospitals’ versus ‘outpatient clinic’; ‘open surgery’ versus ‘endoscopy’; ‘desktop PCs’ versus ‘Sony Playstation’; ‘wireline telephone’ versus ‘mobile telephony’.
The problem is, says Christensen, big companies who listen very well to their customers don’t pay attention to these ‘inferior’ alternatives – because that’s not what their customers want. When the fickle customers suddenly decide that this is what they want – probably due to a credit crunch – the big companies find themselves not being able to offer these alternatives. They can’t keep up.
“Different industry, different values”
The challenge is not only rooted in ‘work culture’ and the ‘modelling’ that follows. There’s valuation to consider, too, which poses a problem to business alliances.
A pharma product is valued on its formulations – ‘hardware’ would be the digital equivalent of this concept. The processes behind the creation of the formulations are protected by patent, among other intellectual property strategies. A mobile phone might be easy to value, but how does one deal with a software application?
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| The Roche Diagnostics Accu-Chek Mobile blood monitoring device. The hardware is very much defined by the software. The 'materiality' of the software is something that pharma has to consider in assigning 'value' to digitality Watch the video Photo: Salina Christmas |
“When we talk to companies in the [IT] space, there’s no manufacturing line to see,” says Beverly Jordan, Vice President, Special Projects and Business Development, AstraZeneca, in the report. “Their ‘manufacturers’ are programmers and developers. How can we truly understand what’s there at the company? How do we assess what their assets are and how much they are worth?”
Again, it’s impossible to put on the usual economist goggle to see what digitality is about. The value of ICT lies in knowledge and creativity. Digitality is an economy geared towards knowledge (k-economy), not just production (p-economy). Copyright is the most popular form of legal protection employed, but open source – often created on the back of crowd-sourcing – is also a form of protection for these ‘creative’ workers. An economy is made on the back of open source – ask Microsoft how XML and Arduino help its proprietary projects.
Despite this awareness, the Ernst & Young report indicated that pharma is hesitant in taking the necessary actions beyond the predictable legal and financial measures.
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| Challenges of creative partnering Click here to see the bigger chart Source: Ernst & Young Progressions survey 2009, p 52 |
Close to 80% of the respondents acknowledge that the biggest challenge in creative partnering with non-traditional entrants lies in corporate strategy, valuation and modelling, and due diligence (see table above). This is understandable given that the pharma corporate practices are slanted towards risk protection (an example: patent). Digital entrepreneurship, however, is slanted towards risk-taking.
Talent is a prerequisite in preparing for the k-economy and the uncertainty the new labour process brings, but the report indicates that the preparedness for ‘talent’ and labour-related issues such as ‘operations’, change management’ and also ‘data security and privacy’ is low.
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| Preparedness for creative partnering challenges Click here to see the bigger chart Source: Ernst & Young Progressions survey 2009, p 53 |
Talent is certainly not identified as a key function essential for CEOs in deal-making, according to the survey.
Trust: It can be a science
So what does it take to prepare for the inevitable?
Janice Haigh, Senior Director, Pricing and Market Access, Astellas Pharma Europe, said at the summit that pharma has to get over its paternalistic attitude. The data-empowered consumers can engage at expert-to-expert level and are more demanding of results.
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| Janice Haigh (pictured, right) says pharma has to get over its paternalistic attitude Reportage: The Economist Pharma Summit 2010 |
However, pharma’s paternalism and aversion towards risks are not without basis – drug trials are not like software trials. Get the formulation wrong and it can cost lives.
Concerns regarding privacy and data protection by the clinicians are also valid, although much has been said about the benefits of trading off privacy over convenience – as discussed at last year’s Informa Mobile Healthcare IT Summit 2009 and as illustrated by Pfizer’s successful rollout of its eCard scheme in Russia, the Phillipines, Malaysia and Indonesia. To date, there are 2.2 million patients in the system, which is to be expanded to Mexico, Brazil and Venezuela.
“I think pharma will lose out to digital,” a delegate from a European pharmaceutical company told us during coffee break. “The business mentality revolves around the ‘hardware’, the drugs, not human communications. Digital businesses put the human interaction before its hardware and software. Digital would win.”
Pharma can’t rely on that tradition of “selling the science”, the report suggests, because it’s no longer enough. Is this true? Does pharma have to ‘lose out’ at all?
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| Bayer's Didget is one of the examples of the medical device technology that is steadily crossing over to pharma, and is taking over the industry with its combination of ICT and engineering capabilities. A delegate tells Clinica that "pharma will lose out" to the digital camp. Reportage: The Economist Pharma Summit 2010 |
“Other members of the health ecosystem sometimes view pharma companies as the enemy,” says Paul Stoffels, Company Group Chairman, Johnson & Johnson, in the report.To create innovative breakthroughs, he says, “we need to foster trust between pharma and the academic and scientific communities”.
Why not use the digital technology as a method of establishing trust among the traditional and non-traditional entrants? For digital businesses, this can be an access point to consider when entering the ecosystem.
In fact, this is what the digital camp is good at. They build technologies on the concepts of crowdsourcing, interaction and knowledge-sharing. An automated supply chain management system is, after all, a method of ensuring that the contract can be fulfilled between the supplier of goods, and the receiver of goods. The hardware and software applications running on this platform, and the connectivity methods linking them, are there to make it possible for ‘trust’ to be audited.
The digital industry, having learnt its painful lessons from technological determinism and obsolescence, have managed to turn this system of belief into a science.


















